foxo4-dri senolytic 2023 Peptide inhibitors targeting FOXO4-p53 interactions and inducing senescent cancer cell-specific apoptosis Frontiers | FOXO4-DRI regulates endothelial
Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway foxo4 dri peptide senolytic mouse study 2023 Molecular modelling of the FOXO4 TP53 interaction to design FOXO4 DRI alleviates age related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice PMC The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging PMC
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